The Reyes lab explores the behaviors, characteristics, and consequences of secreted protein induction by senescent cells in vivo with the ultimate goal to expand our knowledge of creating possibilities for novel therapeutics in the fields of aging and regeneration.

We combine advanced mouse genetic tool, physiology, latest sequencing technologies and quantitative proteomics to determine how senescent cells function throughout region-specific lung microenvironment and how p16INK4a expression contributes to induction of secreted proteins in vivo.

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