Peer Reviewed Articles
Lee JY, Reyes NS, Ravishankar S, Zhou M, Krasilnikov M, Ringler C, Pohan G, Wilson C, Ang, KKH, Wolters PJ, Tsukui T, Sheppard D, Arkin MR, and Peng T. An in vivo screening platform identifies senolytic compounds that target p16INK4a+ fibroblasts in lung fibrosis. JCI 2024, 10.1172/JCI173371
Chen X, Haribowo AG, Baik AH, Fossati A, Stevenson E, Chen YR, Reyes NS, Peng T, Matthay MA, Traglia M, Pico AR, Jarosz DF, Buchwalter A, Chaemmaghami S, Swaney DL, and Jain IH. In vivo protein turnover rates in varying oxygen tensions nominate MYBBP1A as a mediator of the hyperoxia response. Science Advances 2023. 8 Dec 2023 Vol 9, Issue 49 DOI: 10.1126/sciadv.adj48
Reyes NS, Krasilnikov M, Allen NC, Lee JY, Hyams B, Zhou M, Ravishankar S, Cassandras M, Wang C, Khan I, Matatia P, Johmura Y, Molofsky A, Matthay M, Nakanishi M, Sheppard D, Campisi J, Peng T. Sentinel p16(INK4a+) cells in the basement membrane form a reparative niche in the lung. Science. 2022 Oct 14;378(6616):192-201. doi: 10.1126/science.abf3326. Epub 2022 Oct 13. PubMed PMID: 36227993; PubMed Central PMCID: PMC10621323.
Ma N, Reyes de Mochel NR, Pham PD, Yoo TY, Cho KWY, Digman MA. Label-free assessment of pre-implantation embryo quality by the Fluorescence Lifetime Imaging Microscopy (FLIM)-phasor approach. Sci Rep. 2019 Sep 13;9(1):13206. doi: 10.1038/s41598-019-48107-2. PubMed PMID: 31519916; PubMed Central PMCID: PMC6744410.
Wang C, de Mochel NSR, Christenson SA, Cassandras M, Moon R, Brumwell AN, Byrnes LE, Li A, Yokosaki Y, Shan P, Sneddon JB, Jablons D, Lee PJ, Matthay MA, Chapman HA, Peng T. Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype. J Clin Invest. 2018 Oct 1;128(10):4343-4358. doi: 10.1172/JCI99435. Epub 2018 Jul 12. PubMed PMID: 29999500; PubMed Central PMCID: PMC6159975.
Holmes WR, Reyes de Mochel NS, Wang Q, Du H, Peng T, Chiang M, Cinquin O, Cho K, Nie Q. Gene Expression Noise Enhances Robust Organization of the Early Mammalian Blastocyst. PLoS Comput Biol. 2017 Jan;13(1):e1005320. doi: 10.1371/journal.pcbi.1005320. eCollection 2017 Jan. PubMed PMID: 28114387; PubMed Central PMCID: PMC5293272.
Chiang M, Hallman S, Cinquin A, de Mochel NR, Paz A, Kawauchi S, Calof AL, Cho KW, Fowlkes CC, Cinquin O. Analysis of in vivo single cell behavior by high throughput, human-in-the-loop segmentation of three-dimensional images. BMC Bioinformatics. 2015 Nov 25;16:397. doi: 10.1186/s12859-015-0814-7. PubMed PMID: 26607933; PubMed Central PMCID: PMC4659165.
Reyes de Mochel NS, Luong M, Chiang M, Javier AL, Luu E, Toshihiko F, MacGregor GR, Cinquin O, Cho KW. BMP signaling is required for cell cleavage in preimplantation-mouse embryos. Dev Biol. 2015 Jan 1;397(1):45-55. doi: 10.1016/j.ydbio.2014.10.001. Epub 2014 Oct 14. PubMed PMID: 25446538; PubMed Central PMCID: PMC4309750.
Javier AL, Doan LT, Luong M, Reyes de Mochel NS, Sun A, Monuki ES, Cho KW. Bmp indicator mice reveal dynamic regulation of transcriptional response. PLoS One. 2012;7(9):e42566. doi: 10.1371/journal.pone.0042566. Epub 2012 Sep 11. PubMed PMID: 22984405; PubMed Central PMCID: PMC3439458.
Eberlé D, Kim RY, Luk FS, de Mochel NS, Gaudreault N, Olivas VR, Kumar N, Posada JM, Birkeland AC, Rapp JH, Raffai RL. Apolipoprotein E4 domain interaction accelerates diet-induced atherosclerosis in hypomorphic Arg-61 apoe mice. Arterioscler Thromb Vasc Biol. 2012 May;32(5):1116-23. doi: 10.1161/ATVBAHA.112.246389. Epub 2012 Mar 22. PubMed PMID: 22441102; PubMed Central PMCID: PMC3346714.
Gaudreault N, Kumar N, Posada JM, Stephens KB, Reyes de Mochel NS, Eberlé D, Olivas VR, Kim RY, Harms MJ, Johnson S, Messina LM, Rapp JH, Raffai RL. ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):264-72. doi: 10.1161/ATVBAHA.111.238964. Epub 2011 Nov 3. PubMed PMID: 22053073; PubMed Central PMCID: PMC3275345.
Reyes de Mochel NS, Seronello S, Wang SH, Ito C, Zheng JX, Liang TJ, Lambeth JD, Choi J. Hepatocyte NAD(P)H oxidases as an endogenous source of reactive oxygen species during hepatitis C virus infection. Hepatology. 2010 Jul;52(1):47-59. doi: 10.1002/hep.23671. PubMed PMID: 20578128; PubMed Central PMCID: PMC3141587.
Liu RM, Choi J, Wu JH, Gaston Pravia KA, Lewis KM, Brand JD, Mochel NS, Krzywanski DM, Lambeth JD, Hagood JS, Forman HJ, Thannickal VJ, Postlethwait EM. Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts. J Biol Chem. 2010 May 21;285(21):16239-47. doi: 10.1074/jbc.M110.111732. Epub 2010 Mar 12. PubMed PMID: 20228065; PubMed Central PMCID: PMC2871491.
Zhu H, Reyes NS, Meyer MP. Computational and experimental structure-reactivity relationships: evidence for a side reaction in Alpine-Borane reductions of d-benzaldehydes. Tetrahedron Lett. 2009 Dec 9;50(49):6803-6806. doi: 10.1016/j.tetlet.2009.09.109. PubMed PMID: 26989268; PubMed Central PMCID: PMC4792110.
Research Reviews
CJ Cain, DA Conte, ME García-Ojeda, LG Daglio, L Johnson, EH Lau, Reyes, NS...What systems biology is (not, yet) Science 2008, 320 (5879), 1013-1014,112008
NC Allen, NS Reyes, JY Lee, T Peng. Intersection of inflammation and senescence in the aging lung stem cell niche. 2022 Frontiers in Cell and Developmental Biology 2022, 10, 932723